منابع مشابه
Non-coding RNA Era is Dawning
Up to 90% of eukaryotic genomes are transcribed. Only ~ 2% of these transcripts encode proteins, while remaining 98% are ncRNAs [1,2]. ncRNAs can be categorized into infrastructural ncRNAs and regulatory ncRNAs. Constitutively expressed infrastructural ncRNAs include ribosomal RNAs (rRNAs), transfer RNAs (tRNAs), small nuclear RNAs (snRNAs), and small nucleolar RNAs (snoRNAs). Based on their si...
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Summary: SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA associated with cancer pathogenesis. It contributes to a variety of cellular functions and recent evidence propounds its association with autophagy process. It has been showed that SOX2OT can regulate the expression of different autophagy associated factors in human cells with different mechanisms, however more remains to ...
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This issue of the IBM Systems Journal explores a broad set of ideas and approaches to autonomic computing—some first steps in what we see as a journey to create more selfmanaging computing systems. Autonomic computing represents a collection and integration of technologies that enable the creation of an information technology computing infrastructure for IBM’s agenda for the next era of computi...
متن کاملNon-coding RNA: what is functional and what is junk?
The genomes of large multicellular eukaryotes are mostly comprised of non-protein coding DNA. Although there has been much agreement that a small fraction of these genomes has important biological functions, there has been much debate as to whether the rest contributes to development and/or homeostasis. Much of the speculation has centered on the genomic regions that are transcribed into RNA at...
متن کاملNon-coding RNA.
The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a protein, but this does not mean that such RNAs do not contain information nor have function. Although it has been generally assumed that most genetic information is transacted by proteins, recent evidence suggests that the majority of the genomes of mammals and other complex organisms is in fact transcribed into...
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ژورنال
عنوان ژورنال: SOJ Surgery
سال: 2014
ISSN: 2376-4570
DOI: 10.15226/2376-4570/1/1/00102